A requirement of Caveolin-1 in the regulation of TRPC1 mediated [Ca.sup.2+] entry.
AIM: To investigate the regulation of TRPC1 by Caveolin1 and lipid rafts. RATIONALE: "Caveolae" are cholesterol rich specialized plasma membrane domains with Caveolin1 (Cav1) as their major structural protein. These membrane domains constitute a major cellular compartment that facilitates various signal transduction events, [Ca.sup.2+] influx being one...

Language and regional differences in evaluations of Medicare managed care by Hispanics.
The Medicare + Choice program was aimed at increasing the managed care options among Medicare beneficiaries. Although the program has not achieved the enrollment envisioned by policy makers, there were approximately 5 million (12 percent) Medicare beneficiaries enrolled in Medicare+Choice in 2004 (KFF 2005). This program has been particularly...

A qualitative study of common functional problems experienced by people with complete ulnar nerve paralysis.
Summary Objectives To identify the most common functional problems caused by ulnar nerve palsy. This study is the first phase in the process of developing a patient-centred hand function questionnaire specific for ulnar palsy. Design Twenty-five participants with complete irreversible ulnar nerve palsy were asked...

The prisoner's ombudsman: protecting constitutional rights and fostering justice in American corrections.
The Spirit of Christ, the Redeemer of the world, must breathe even where people are chained in prisons according to the logic of a still necessary human justice. Punishment cannot be reduced to mere retribution, much less take the form of social retaliation or a sort of institutional vengeance....

Abortion: freedom and responsibility in the 21st century: a roundtable conversation.
[ILLUSTRATION OMITTED] IN LATE FEBRUARY, CATHOLICS FOR CHOICE SPONSORED a roundtable conversation on recent political, ethical, moral and social developments in the abortion debate. DRAWING A PARALLEL TO JOHN Muir's environmental writing that purports everything in the universe is related to everything else, moderator Denise...

Chloroquine: novel uses & manifestations.
Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the treatment of malaria in the 1930s. CHQ has, however, since accrued a plethora of uses in the treatment and amelioration of several other diseases and conditions because of its lysosomotropic properties. It also has characteristic physiological...

[[alpha].sub.1A] adrenergic receptors regulate neurogenesis and cognitive function.
The adrenergic system is involved in many physiological functions including learning and memory, stress and anxiety, mood and appetite. A major target of this system is the hippocampus, a region that is critically important for learning and memory. Recent studies have suggested that alpha-1A adrenergic receptors ([alpha]1A-ARs) may regulate...

8. Evidence-based medicine (EbM) versus health services research: how is complementary oncology represented therein?
Oncological therapy approaches are measured by hard outcome parameters like survival time, quality of life or at best by the relation of survival time and quality of life (health-adjusted life years or quality-adjusted life years). Surrogate markers like response under therapy (complete remission, partial remission) or time to progression...

Predicting changes in staff morale and burnout at community health centers participating in the health disparities collaboratives.
The introduction of quality improvement (QI) initiatives can present special challenges for health care settings that have limited personnel and financial resources, and high attrition among key staff. In the context of such constraints, the difficulty of balancing daily clinical demands with additional QI responsibilities can lead to lowered...

New Reports in New England Journal of Medicine & Journal of School Health Support Mental Health Screening for Youth.
NEW YORK, Jan. 22 /PRNewswire/ -- The prestigious New England Journal of Medicine and the American School Health Association's Journal of School Health have published articles supporting a national initiative for mental health screening and cite Columbia University's TeenScreen Program. "When implemented with appropriate family, school, and...