Inspire Reports Update on Cystic Fibrosis Clinical Program.
HEALTH AND BEAUTY CLOSE-UP-2 August 2008-Inspire Reports Update on Cystic Fibrosis Clinical Program(C)2008 - CloseUpMedia - newsdesk@closeupmedia.com Inspire Pharmaceuticals announced modifications to the clinical protocol for TIGER-2, the Company's ongoing second Phase 3 trial with denufosol tetrasodium for the treatment of cystic fibrosis (CF). In...

Woman seeks lung donor; Cystic fibrosis victim goes west.
Byline: Brian Lee Charlton A 25-year-old Charlton woman is waiting to receive a lung transplant at the University of Southern California's Keck School of Medicine. Lila S. Smith, who has cystic fibrosis, went west last month with her husband, Lucas I. Harms, 27,...

Comparison of High-Frequency Chest Wall Oscillation With Differing Waveforms for Airway Clearance in Cystic Fibrosis.
Background: High-frequency chest wall oscillation (HFCWO) is commonly used by cystic fibrosis (CF) patients for airway clearance. The primary objective of this study was to determine whether the use of a newer HFCWO device that generates oscillations with a triangular waveform results in greater sputum production than a commonly...

Oral drug for cystic fibrosis shows promise in early trials.
A drug for fixing a crucial defective protein in cystic fibrosis improved patients' lung function and sweat chloride levels, according to early results from a small randomized study. The investigational oral drug, VX-770, is still in phase II trials. But preliminary findings in 20 patients--particularly the impact...

Take a breath: fatty substance may play role in cystic fibrosis.
Accumulation of a fatty compound called ceramide in the lungs could set the stage for the chronic lung infections of cystic fibrosis, a study in mice suggests. The finding offers a new twist on the still-unresolved course of this hereditary disease. Patients with cystic fibrosis have a...

States rapidly adopting cystic fibrosis screening in newborns.
SALT LAKE CITY -- Twenty-nine states required newborn cystic fibrosis screening as of this past summer, and more states are likely to do so soon, Dr. Michael Rock said at the annual meeting of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. "Cystic fibrosis newborn...

Cystic Fibrosis Foundation Invests More Than $3 Million to Expand Clinical Research Capabilities Nationwide.
Patient Participation in Clinical Trials Key to Discovery of New Treatments WASHINGTON, Feb. 5 /PRNewswire-USNewswire/ -- To enable greater patient involvement in clinical drug trials, and speed the development of new therapies, Cystic Fibrosis Foundation Therapeutics Inc. (CFFT), a nonprofit affiliate of the Cystic Fibrosis Foundation, announced...

Exercise testing and training with the young cystic fibrosis patient.
Abstract The purpose of the article is to review the literature related to exercise and Cystic fibrosis (CF), with particular focus on the young CF patient. Exercise intolerance is a characteristic of CF, however, recent studies in adults have advanced our understanding of how exercise can be...

Vitamins A and E and pulmonary exacerbations in patients with cystic fibrosis.
Vitamins A and E and pulmonary exacerbations in patients with cystic fibrosis. Hakim 17, Kerem E, Rivlin J, Bentur L. J Pediatr Gastroenterol Nutr 2007;45:347-353. BACKGROUND: Increased levels of oxidative stress result in pulmonary damage contributing to the development of chronic lung disease in cystic fibrosis (CF)....

Surgery boosts lung function in cystic fibrosis.
ORLANDO -- Laparoscopic Nissen fundoplication was able to maintain or improve pulmonary function in 14 children with severe gastroesophageal reflux disease and cystic fibrosis, Dr. Sean J. Barnett and his associates reported in a poster at the annual meeting of the American Pediatric Surgical Association. Children with...