Hemolytic uremic syndrome.
A.P., a 42-year-old woman, presented with rectal bleeding to her primary care physician. Endoscopic examination revealed a mass in the anal canal. Biopsy was positive for squamous cell carcinoma. A.P. underwent local excision and was established as stage II (T2N0M0). After surgery, she received 5-fluorouracil (FU) 1,000 mg/[m.sup.2] by...

Human coronary artery effect of stent geometry on phase shift between pressure and flow waveforms in stented.
INTRODUCTION Atherosclerosis is patchy intimal plaques (atheromas) in medium and large arteries. The plaques contain lipids, inflammatory cells, smooth muscle cells, and connective tissue. Risk factors for this disease include dyslipidemia, diabetes, cigarette smoking, family history, sedentary lifestyle, obesity, hypertension, and hemodynamic. Atherosclerosis can affect all large...

Disease associations of mannose-binding lectin & potential of replacement therapy.
Mannose-binding lectin (MBL) is an important component of the immune defence able to bind to repeating mannose based structural patterns typical of microbial surface (bacteria, viruses, fungi, parasites) leading to opsonization and phagocytosis, and activation of the complement pathway resulting in lysis of the pathogen. MBL thus plays a...

Transfusion outcomes differ between children and adults.
HUNTINGTON BEACH, CALIF. -- Although immunosuppression appears to be a consequence of blood-product transfusion in critically ill adults, a study suggests that blood transfusions do not increase morbidity or mortality in critically ill children. Infection rates were significantly higher in children who received blood products than in...

Coagulation factors may predict thrombosis risk.
ATLANTA -- Women who opt for hormone therapy to ease their discomfort from hot flashes and other menopausal symptoms often do so without knowing their risk of developing adverse effects. Now, data from the Women's Health Initiative trials of hormone therapy (HT) may help women make more...

GammaCan Inks Supply Pact with Bio Products Laboratory.
HEALTH AND BEAUTY CLOSE-UP-29 June 2008-GammaCan Inks Supply Pact with Bio Products Laboratory(C)2008 - CloseUpMedia - newsdesk@closeupmedia.com GammaCan International, a developer of proprietary immunotherapies for the treatment of melanoma and other cancers, recently announced that the Company s subsidiary has entered into a manufacturing agreement with Bio...

FDA approves sealant for grafting over burn sites.
A fibrin sealant recently approved by the Food and Drug Administration for adhering autologous skin grafts in pediatric and adult burn patients provides an alternative to staples and sutures, according to the agency. The sealant, derived from pooled human plasma, will be available in July and will...

Maxygen Gets Approval for Clinical Trial of Factor VIIa in the UK.
HEALTH AND BEAUTY CLOSE-UP-13 June 2008-Maxygen Gets Approval for Clinical Trial of Factor VIIa in the UK(C)2008 - CloseUpMedia - newsdesk@closeupmedia.com Maxygen announced that it has filed a Clinical Trial Authorization (CTA) and received the necessary approvals in the United Kingdom to initiate a first-in-human Phase I...

Haemacure Exec to Speak at BioFinance Conference.
HEALTH AND BEAUTY CLOSE-UP-1 May 2008-Haemacure Exec to Speak at BioFinance Conference(C)2008 - CloseUpMedia - newsdesk@closeupmedia.com Haemacure, a Montreal-based specialty bio-therapeutics company developing high-value human plasma-derived protein products for commercialization, announced that Joseph Galli, Chairman and Chief Executive Officer, will present at BioFinance 2008 on Thursday, May...

Viable human blood substitute found?
Every three seconds, someone, somewhere in the U.S. needs a blood transfusion, and one in three people will need a blood transfusion in his or her lifetime. In developing countries, an average of 25% of blood in blood banks is contaminated. In the U.S. and Canada, about two percent...